The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2016
Surgical treatment of congenital cystic adenomatoid malformation: a retrospective study of single tertiary center experience.
СтатьяНазвание и аннотация: Перевод в очереди
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Xia Bo, Yu Gang, Liu Cuifen, Hong Chun, Tang Jing
Аннотация
OBJECTIVE: To summarize the experience drawn from treatment of fetus with congenital cystic adenomatoid malformation (CCAM).
METHODS: This retrospective report has reviewed a clinical history of 115 patients with CCAM from September 2012 to June 2014. All cases were divided into two groups according to symptomatology: group A (n = 96, asymptomatic group) and group B (n = 19, symptomatic group). Major factors were compared between two groups. Numerical data were presented as the median (range). The difference between median was performed with ANOVA.
RESULTS: The mean gestational age of prenatal diagnosis was 24.3 weeks (range, 17-36). 49 cases with CCAM volume ratio (CVR) were retrospectively analyzed, with a median max CVR of 0.95 (range, 0.19-3.2), In the 115 cases, mean operation age was (3.7 ± 0.32) months old. Symptom is significantly associated with lesion size and chest radiographs (CXR) (p < 0.05). Compared with symptomatic CCAM patients, asymptomatic patients were associated with better clinical outcome.
CONCLUSIONS: The value of CVR to evaluate prognosis showed no statistical significance. Although CXR are not reliable indicators to assess the lesion, it can predict the emergency situation. Due to potential trend of symptomatic and poor postoperative symptoms group, early postnatal CT scan and early surgical treatment are suggested.
METHODS: This retrospective report has reviewed a clinical history of 115 patients with CCAM from September 2012 to June 2014. All cases were divided into two groups according to symptomatology: group A (n = 96, asymptomatic group) and group B (n = 19, symptomatic group). Major factors were compared between two groups. Numerical data were presented as the median (range). The difference between median was performed with ANOVA.
RESULTS: The mean gestational age of prenatal diagnosis was 24.3 weeks (range, 17-36). 49 cases with CCAM volume ratio (CVR) were retrospectively analyzed, with a median max CVR of 0.95 (range, 0.19-3.2), In the 115 cases, mean operation age was (3.7 ± 0.32) months old. Symptom is significantly associated with lesion size and chest radiographs (CXR) (p < 0.05). Compared with symptomatic CCAM patients, asymptomatic patients were associated with better clinical outcome.
CONCLUSIONS: The value of CVR to evaluate prognosis showed no statistical significance. Although CXR are not reliable indicators to assess the lesion, it can predict the emergency situation. Due to potential trend of symptomatic and poor postoperative symptoms group, early postnatal CT scan and early surgical treatment are suggested.
Предметные рубрики MeSH
Analysis of VarianceCystic Adenomatoid Malformation of Lung, CongenitalFemaleGestational AgeHumansInfantInfant, NewbornLength of StayMagnetic Resonance ImagingMaleRadiographyRetrospective StudiesSeverity of Illness IndexTertiary Care CentersTime FactorsTomography, X-Ray ComputedUltrasonography, Prenatal