Mortality among type 2 diabetic individuals and associated risk factors: the Three City Study.

The 10 year mortality experience was determined in a population-based cohort of 540 Type 2 diabetic individuals. The association between potential risk factors and all causes mortality was examined. Diabetes was not mentioned anywhere on the death certificate in 46% of 274 decedents. Diseases of the circulatory system (ICD9-390-459) accounted for the majority (62%) of deaths in this cohort. Ten-year survival was poorer than expected for both men and women compared to the age- and sex-matched Minnesota population. Standardized mortality ratios for selected causes of death indicated excess for cardiovascular disease (ICD9-390-459), coronary heart disease (ICD9 410-414) and cerebrovascular disease. Baseline variables associated with all causes of mortality included age and a history of macrovascular disease. These findings indicate that mortality data significantly underestimate the magnitude of diabetes and that individuals with diabetes have poorer survival than non-diabetic individuals.