The first year of the toxicology program.

The CAP Toxicology Survey Program's initial year is reviewed. Four series of samples, each consisting of five specimens with approximately 12 different drugs, were sent to almost 200 participants and as many as seven referees. They reported the presence or absence of more than 16 different compounds, and identified specific barbiturates when present. In each series, two serum samples were for qualitative identification and quantitative analysis. The remainder were urine samples for qualitative analysis. The aim of the survey is to enhance the "current state of the art" among participants. Drug-abuse toxicology and therapeutic monitoring of drugs were given priority. Clinically relevant samples reflecting current drug abuse, especially mixed-drug abuse, were provided, including serum for quantitative determination as is required in treatment of barbiturate overdose and for therapeutic drug monitoring. The Committee has interacted with participants by critiques of surveys, by questionnaires, and by responding to queries from participants.