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Войти в исследования Fertility and sterility · 2009
Monozygotic twins in infertile patients with advanced maternal age: case reports and review of the literature.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Esfandiari Navid, Kapoor Monica, Burjaq Hasan, Chang Paul, Gotlieb Lynda, Casper Robert F
Аннотация
OBJECTIVE: To report two cases of successful monozygotic twin pregnancies in women undergoing infertility treatment and to review possible etiologic factors.
DESIGN: Case report and review of the literature.
SETTING: University of Toronto-affiliated infertility clinic.
PATIENT(S): A 43-year-old woman and a 44-year-old woman with history of secondary infertility.
INTERVENTION(S): In vitro fertilization and ET.
MAIN OUTCOME MEASURE(S): Monozygotic twin pregnancy.
RESULT(S): Delivery of two sets of monozygotic twins.
CONCLUSION(S): The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching.
DESIGN: Case report and review of the literature.
SETTING: University of Toronto-affiliated infertility clinic.
PATIENT(S): A 43-year-old woman and a 44-year-old woman with history of secondary infertility.
INTERVENTION(S): In vitro fertilization and ET.
MAIN OUTCOME MEASURE(S): Monozygotic twin pregnancy.
RESULT(S): Delivery of two sets of monozygotic twins.
CONCLUSION(S): The only identified potential risk factors for monozygotic twins are maternal age and assisted reproductive technologies. Both patients reported here were aged >40 years and underwent assisted reproduction procedures, including high-dose gonadotropin stimulation, embryo culture, and, in case 2, intracytoplasmic sperm injection plus assisted hatching.