[Diffuse myometrial hypertrophy. Cause of abnormal uterine bleeding. Clinico-pathological study of 4 cases and review of the literature].

Difusse uterine myohipertrophy (DUMH) is a condition characterized by the presence of homogeneous and diffuse uterine enlargement in the absence of myoendometrial cause of bleeding. Today there is insufficient data to conclude that DUMH is a distinct clinicopathological entity. It is characterized by: 1) Uterine weight of more that 200 g, 2) a myometrial thickness of more that 2.0 cm and 3) the absence of any endomyometrial cause of bleeding. In DUMH the increased thickness of the myometrium is due to hypertrophy of the muscle cells with no increase in fibroconnective intersticial tissue and the bleeding secondary to increase endometrial area and abnormal myometrium contraction. We report 4 cases of DUMH seen at the ABC Hospital.