Acta medica portuguesa · 2013
[Neonatal seizures in a tertiary neonatal intensive care unit].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Lopes Andreia, Vilan Ana, Guedes Maria Beatriz, Guimarães Hercília
Аннотация
INTRODUCTION: Seizures are frequent in the neonatal period. They can be idiopathic, be caused by organic brain anomalies or by metabolic disturbances.
OBJECTIVE: Evaluation of the etiologic diagnosis and clinical evolution of the newborns with neonatal seizures admitted at one tertiary neonatal intensive care unit.
MATERIAL AND METHODS: Retrospective review of the clinical files of the newborns with neonatal seizures, during a period of eight years.
RESULTS: Neonatal seizures occurred in 91 cases. Seventy nine (86.8%) received anticonvulsant therapy during clinical seizure. Image and/or electrophysiological studies were performed in the majority of newborns (86.8%). Etiology was identified in 51.6% of the 91 cases studied, being the more frequent situations: central nervous system bleeding (11 cases), hypoxic-ischemic encephalopathy (10 cases) and electrolytes disturbances (7 cases). Mortality rate was 16.5%. The newborns followed in our hospital had good neurodevelopment, in 70.2% of cases but in 10.6% was detected important neurodevelopment impairment, including cerebral palsy.
CONCLUSIONS: Anomalies in the cranial ultrasound and in the electroencephalography were correlated with clinical evolution. They still are first line exams in the initial approach to this pathology.
OBJECTIVE: Evaluation of the etiologic diagnosis and clinical evolution of the newborns with neonatal seizures admitted at one tertiary neonatal intensive care unit.
MATERIAL AND METHODS: Retrospective review of the clinical files of the newborns with neonatal seizures, during a period of eight years.
RESULTS: Neonatal seizures occurred in 91 cases. Seventy nine (86.8%) received anticonvulsant therapy during clinical seizure. Image and/or electrophysiological studies were performed in the majority of newborns (86.8%). Etiology was identified in 51.6% of the 91 cases studied, being the more frequent situations: central nervous system bleeding (11 cases), hypoxic-ischemic encephalopathy (10 cases) and electrolytes disturbances (7 cases). Mortality rate was 16.5%. The newborns followed in our hospital had good neurodevelopment, in 70.2% of cases but in 10.6% was detected important neurodevelopment impairment, including cerebral palsy.
CONCLUSIONS: Anomalies in the cranial ultrasound and in the electroencephalography were correlated with clinical evolution. They still are first line exams in the initial approach to this pathology.