Early induction of abortion by a combination of oral mifepristone and misoprostol administered by the vaginal route.

Medically induced abortion using a new regimen of oral mifepristone 600 mg and vaginal misoprostol 800 micrograms (PGE1 analogue) was carried out in 100 women. Abortion occurred in all patients without resort to surgery. In 99 women, the abortion occurred within 4 hours of the administration of the prostaglandin. Sixty-seven patients did not request any form of analgesia. This regimen is highly effective, has a low incidence of side effects (mainly gastrointestinal) and appears to be highly acceptable to women.