Retinal cases & brief reports · 2026
Multimodal imaging of ASHH in a case of Scrub Typhus Retinopathy.
СтатьяНазвание и аннотация: Перевод в очереди
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Ray Paulomi, Rajkumar Aarti, Thaliath Annu Teres, Lakshmi Praveena Racharla Sree, Bhaskar Dhonnar Abhijit, Gokhale Sarang Nikhil, Biswas Anamika, Mohapatra Ayushi, Sen Ahana, Roy Rupak
Аннотация
PURPOSE: To report a case of scrub typhus retinopathy presenting with angular sign of Henle layer hyperreflectivity (ASHH) on optical coherence tomography (OCT).
METHODS: This is a retrospective case report with multimodal imaging.
RESULTS: A 43-year-old Indian man presented with sudden, painless diminution of vision in both eyes,(left more than right) following a febrile illness. He was diagnosed with scrub typhus based on positive IgM ELISA. Fundus examination revealed scattered intraretinal haemorrhages in both eyes and a yellowish foveal lesion in the left eye. Optical coherence tomography (OCT) demonstrated angular sign of Henle layer hyperreflectivity (ASHH) in both eyes, with a hard exudate clump at the fovea in the left eye and corresponding areas of blocked fluorescence on fluorescein angiography. A diagnosis of scrub typhus retinopathy was made. After treatment with oral corticosteroids, at one-month follow-up, visual acuity, with marked resolution of haemorrhages and regression of ASHH on OCT.
CONCLUSION: Scrub typhus can present with retinopathy associated with ASHH, a marker of deep retinal ischemia. Multimodal imaging, particularly OCT, plays a crucial role in identifying ischemic retinal changes and may help in assessing disease severity and visual prognosis.
METHODS: This is a retrospective case report with multimodal imaging.
RESULTS: A 43-year-old Indian man presented with sudden, painless diminution of vision in both eyes,(left more than right) following a febrile illness. He was diagnosed with scrub typhus based on positive IgM ELISA. Fundus examination revealed scattered intraretinal haemorrhages in both eyes and a yellowish foveal lesion in the left eye. Optical coherence tomography (OCT) demonstrated angular sign of Henle layer hyperreflectivity (ASHH) in both eyes, with a hard exudate clump at the fovea in the left eye and corresponding areas of blocked fluorescence on fluorescein angiography. A diagnosis of scrub typhus retinopathy was made. After treatment with oral corticosteroids, at one-month follow-up, visual acuity, with marked resolution of haemorrhages and regression of ASHH on OCT.
CONCLUSION: Scrub typhus can present with retinopathy associated with ASHH, a marker of deep retinal ischemia. Multimodal imaging, particularly OCT, plays a crucial role in identifying ischemic retinal changes and may help in assessing disease severity and visual prognosis.