Isotachophoretic and immunological analysis of venoms from sea snakes (Laticauda semifasciata) and brown recluse spiders (Loxosceles reclusa) of different morphology, locality, sex, and developmental stages.

Sea snake venom: The venom compositions of sea snakes, Laticauda semifasciata, with different scale patterns were analyzed by isotachophoresis. The comparison showed quantitative rather than qualitative differences. Similarly, L. semifasciata venoms of Philippine and Japanese origins differed only in the quantity of certain proteins. Spider venom: 3. Loxosceles reclusa venom apparatus extract is rich in neutral and acidic proteins but contains relatively small quantities of basic proteins. Differences in venom apparatus extract composition between nymph and adult (male or female) were detected by isotachophoresis. The extracts of male and female venom apparatus were very similar. Extracts of venom apparatus of spiders collected in locations separated by 100 miles were the same.