Медицинская библиотека · IDCases · 2025

Rickettsia sp. DNA recovered from a febrile patient from Papua, Indonesia.

Johar Edison, Sriyani Ida Yus, Dewi Yora Permata, Puspitasari Agatha Mia, Nisa Fahira Ainun, Amalia Ristya, Kariodimedjo Pinkan Pertiwi, Poespoprodjo Jeanne Rini, Kenangalem Enny, Yudhaputri Frilasita Aisyah, Trianty Leily, Ledermann Jeremy P, Myint Khin Saw Aye, Mossel Eric C, Powers Ann M, Noviyanti Rintis

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Аннотация

BACKGROUND

Rickettsia are neglected, arthropod-borne bacteria causing febrile illness of varying severity. Indonesia is endemic for several Rickettsia species, predominantly from murine and scrub typhus groups.

OBJECTIVE

We described here a potentially novel Rickettsia species in a young adult presenting with acute, undifferentiated, febrile illness at a primary health center in Timika, Papua, Indonesia, in 2021.

METHODS

Blood tested positive for Rickettsia spp. by a nucleic acid amplification test, 17-kDa and ompB gene fragments were successfully sequenced.

RESULTS

The recovered sequences showed the highest similarity to two Rickettsia spp. of mosquito origin, with 90.0% identity for the 17-kDa and 85.6% for the ompB gene.

CONCLUSION

These findings suggest the presence of a divergent Rickettsia lineage in Papua, Indonesia. To our knowledge, this is the first report of Rickettsia DNA sequences obtained from a human case in this region.

Для цитирования: Johar Edison, Sriyani Ida Yus, Dewi Yora Permata, Puspitasari Agatha Mia, Nisa Fahira Ainun, Amalia Ristya, Kariodimedjo Pinkan Pertiwi, Poespoprodjo Jeanne Rini, Kenangalem Enny, Yudhaputri Frilasita Aisyah, Trianty Leily, Ledermann Jeremy P, Myint Khin Saw Aye, Mossel Eric C, Powers Ann M, Noviyanti Rintis. Rickettsia sp. DNA recovered from a febrile patient from Papua, Indonesia.. IDCases. 2025. DOI: 10.1016/j.idcr.2025.e02298.

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