Biulleten' eksperimental'noi biologii i meditsiny · 1984
[Endocrine and metabolic mechanisms of the pathological syndrome due to antigens of homologous glial tissue in monkeys].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Cupić D, Krzalić Lj, Nastić-Mirić D, Korneva E A, Shkhinek E K
Аннотация
Monkeys (Macaca mulatta) of both sexes repeatedly immunized with a complex of glial antigens of the homologous brain demonstrated abnormalities of hormonal functions after 1 to 5 weeks. These abnormalities were marked by a decrease in the total serum tyroxine (after 1 week) and a rise in the concentration of 11-hydroxycorticosteroids (11-OHCS) that occurred after 5 weeks. The changes in tyroxine level were more stable than those in the concentration of 11-OHCS. The immunized animals manifested changes in the disc electrophoregram of the serum. Application of stress resulted in a consistent elevation of the concentration of 11-OHCS and in temporary changes in the number and intensity of individual fractions of serum proteins. The fractional composition of serum proteins was different in control and experimental monkeys.