Maternal plasma testosterone levels in molar pregnancy.

Plasma testosterone levels in 14 patients with intact molar pregnancy were found to be elevated compared to patients with normal pregnancies of corresponding gestation. The plasma testosterone concentration ranged from 2-0 to 8-4 ng/ml with a mean +/- SE of 5-2 +/- 0-5 ng/ml. After evacuation of the uterus, there was a significant fall in plasma testosterone levels which ranged from 1-6 to 5-9 ng/ml with a mean +/- SE of 3-2 +/-0-3 ng/ml. The trophoblast might have been the source of extra testosterone in molar pregnancy.