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DOI 10.1046/j.1460-9568.2003.02432.x

Медицинская библиотека · Clinical and experimental rheumatology · 2008

IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behçet's disease in patients of German or Turkish origin.

Pérez-Martín M, Cifuentes M, Grondona J M, Bermúdez-Silva F J, Arrabal P M, Pérez-Fígares J M, Jiménez A J, García-Segura L M, Férnandez-Llebrez P, P. Fernández-Llebrez

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Аннотация

STUDY

DESIGN

Cohort study.

OBJECTIVES

To describe calf muscle endurance recovery and to explore factors predictive of poor calf muscle endurance recovery 1 year after surgical repair of an Achilles tendon rupture (ATR).

BACKGROUND

ATR is a common sports-related injury and is often managed with open surgical repair. After ATR repair most patients return to usual activities 6 months after surgery. However, calf endurance impairment can persist up to 6 years, possibly impacting performance of daily activities and sport.

METHODS

A secondary analysis of a 73-patient cohort from a randomized controlled trial assessing the effects of early weight bearing after surgical repair of an ATR was performed. Calf muscle endurance recovery was measured by single-heel raises using a customized counting device at 6 months and 1 year postoperatively. Descriptive statistics were used to outline recovery of calf muscle endurance. Physical and patient-reported outcomes were examined for their association with calf-muscle endurance recovery. Multiple linear regression analysis was performed to explore variables associated with recovery of calf endurance 1 year postoperatively.

RESULTS

Mean recovery of calf muscle endurance was 76% at 1 year. Multivariate regression analysis showed an association of being female, reporting no resting pain at 3 months, and physical functioning and calf endurance at 6 months, with better recovery of calf endurance at 1 year.

CONCLUSIONS

Calf muscle endurance at 1 year remained impaired in a considerable portion of the sample. Pain, gender, and physical functioning are likely important factors in determining recovery of calf muscle endurance.

LEVEL OF EVIDENCE: Prognosis, level 2b.J Orthop Sports Phys Ther 2010;40(6):345-351, Epub 15 April 2010. doi:10.2519/jospt.2010.3204.

Для цитирования: Pérez-Martín M, Cifuentes M, Grondona J M, Bermúdez-Silva F J, Arrabal P M, Pérez-Fígares J M, Jiménez A J, García-Segura L M, Férnandez-Llebrez P, P. Fernández-Llebrez. IL-6 receptor, IL-8 receptor and TNF-alpha238 (G/A) polymorphisms are not associated with Behçet's disease in patients of German or Turkish origin.. Clinical and experimental rheumatology. 2008. DOI: 10.1046/j.1460-9568.2003.02432.x.

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