Revista da Sociedade Brasileira de Medicina Tropical · 2019
Brazilian Spotted Fever Prevention through a Nonlethal Capybara Population Control Strategy.
СтатьяНазвание и аннотация: Перевод в очереди
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Rosenfield Derek Andrew, Polo Gina, Pizzutto Cristiane Schilbach
Аннотация
INTRODUCTION: Brazilian spotted fever (BSF), a lethal tick-borne Rickettsioses (2000 - 2018 >600 human deaths) involving synanthropic capybara as host.
METHODS: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.
RESULTS: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.
CONCLUSIONS: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.
METHODS: We introduced an alternative to mitigate human-capybara conflicts and epidemiologic concerns of BSF. Complex aspects like transmission dynamics, risk areas, host mobility, and birth rate control, were considered to develop a prevention strategy using an anti-GnRH vaccine.
RESULTS: The propositioned immunocontraceptive potentially remove and prevent the spread of BSF from endemic areas.
CONCLUSIONS: We propose the anti-GnRH vaccine as a BSF prevention strategy based on these favorable results.