Potentiated reagin response to egg albumin in Nippostrongylus brasiliensis infected rats. 3. Further studies on the time course of the reagin response.

The potentiating effect of Nippostrongylus brasiliensis infection on the serum levels of reagin present in rats sensitized with egg albumin and Bordetella pertussis vaccine was examined to show at which stages following sensitization the increased response could be provoked by infection. It was found that the potentiated titres of anti-egg albumin rat reagin were related to those levels of egg albumin reagin present at the time of infection. Re-infection with N. brasiliensis appeared to prolong the presence of high levels of circulating rat reagin to egg albumin.