Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2000
[Clinical pathology of Dubin-Johnson syndrome].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Luo Z, Zhang L, Li Y
Аннотация
OBJECTIVE: To investigate the property of pigment granules in the hepatocytes in patients with Dubin-Johnson syndrome.
METHOD: Light microscopy, histochemical, immnohistochemical and electron microscopy techniques were used to study the pigment glanules and the expression of S-100 protein and HMB45 in hepatocytes.
RESULTS: Histological examination revealed normal lobular architecture and the abundont brown pigments which were chiefly seen in the centrilobular zone hepatocytes. The pigment granules were evidenced to have the characterization of both lipofuscin and melanin by histochemical staining and ultrastructural studies and to have the featurts of the melanin by immnohistochemical staining.
CONCLUSION: The results suggest that the pigment graunles are lipfuscin-melanin complex in the hepatocytes in patients with Dubin-Johnson syndrome.
METHOD: Light microscopy, histochemical, immnohistochemical and electron microscopy techniques were used to study the pigment glanules and the expression of S-100 protein and HMB45 in hepatocytes.
RESULTS: Histological examination revealed normal lobular architecture and the abundont brown pigments which were chiefly seen in the centrilobular zone hepatocytes. The pigment granules were evidenced to have the characterization of both lipofuscin and melanin by histochemical staining and ultrastructural studies and to have the featurts of the melanin by immnohistochemical staining.
CONCLUSION: The results suggest that the pigment graunles are lipfuscin-melanin complex in the hepatocytes in patients with Dubin-Johnson syndrome.