[Medium molecular weight molecules and their fractions in Astrakhan rickettsial fever].

The level of medium-weight molecules (MWM) over the course of disease and changes in the lipid share of MWM fractions at the peak of disease were studied in patients with Astrakhan rickettsial fever (ARF). The level of MWM was significantly increased in comparison with the control and MWM concentration clearly correlated with the severity of intoxication. A level higher than 600 U is an unfavorable sign of a grave course. The significance of the lipid part of MWM fraction in the formation of the intoxication syndrome in ARF is shown.