Involvement of choroid plexuses in neurosarcoidosis.

A 43-year-old woman, known to have suffered from chronic multisystem sarcoidosis since the age of 28, developed a posterior fossa mass and obstructive hydrocephalus 2 years before death. At autopsy she was found to have hydrocephalus involving all four ventricles, mass lesions in the brain stem and cerebellum, and severe involvement of the choroid plexuses. The optic nerves and chiasm were also infiltrated with granulomas. Only minimal lesions were found in other parts of the brain.