[Local sorption therapy and its effectiveness in correction of endogenous intoxication in patients with acute purulent pyelonephritis and paranephritis].

The 118 operated patients with different forms of acute purulent pyelonephritis, including complicated with paranephritis were followed-up. Control group consisted of 65 similar patients who underwent traditional comprehensive treatment. Study group (n = 53) underwent additional wound dialysis with carbonic drainage-sorbent. Comparative analysis of the efficiency of the proposed method of drainage was carried out according to the clinical and laboratory parameters. The use of sorption therapy in patients with purulent and destructive forms of pyelonephritis and paranephritis allowed to reduce postoperative complications in patients of study group by 11%, as confirmed by the positive dynamics of the proinflammatory and anti-inflammatory cytokines. Moreover, the effectiveness of wound dialysis is justified by accelerated rehabilitation of patients and the possibility of discharge for 3 days before the control group of patients. The efficacy of wound dialysis (pyosorbtion) was equal to 18%.