Left ventricular end-diastolic volume in advanced ischemic heart disease; comparison between healthy subjects and patients with mitral stenosis.

The left ventricular end-diastolic volume (EDV), end-systolic volume (ESV) and systolic ejection fraction (SV/EDV) were determined in 6 healthy subjects, 21 patients with ischemic heart disease and 8 patients with mitral stenosis by the left ventricular 133Xe washout technique. Cardiac and stroke indexes as well as left ventricular work and stroke work indexes do not differ in all three groups. A significantly higher EDV and ESV together with a low SV/EDV suggested impaired left ventricular function in patients with ischemic heart disease.