Effect of Some Immunological Markers on The Level of Anti- Mullerian Hormone (AMH) in Women Infected with Toxoplasma gondii.

OBJECTIVE

Aim: To study effect of T. gondii infection on levels of immunological parameters for possible effects that may appear in infected women in the future, and to study direct correlation of infection in raising AMH value.

PATIENTS AND

METHODS

Materials and

Methods

80 blood samples were collected and divided into two equal groups. Of unmarried women, their ages ranged from 20-25: 1st group was from infected with Toxoplasma who visited health institutions, 2nd group was from whom were not infected as a control group. Toxoplasma infection was diagnosed using the LAT test and the ELISA test. Detection of human IL-2, IL-10 and IL-12 (pg/ml) ELISA KIT, Assay Max Human was conducted according to manufacturing company.

RESULTS

Results

An increase in the level of human IL-2, IL-10 and IL-12 (pg/ml) in infected women compared to control group. A positive correlation of the human IL-2, IL-10 and IL-12 (pg/ml) with AMH level, which supports possibility of adopting AMH level as an indicator of cases of polycystic ovary cysts and infertility in future.

CONCLUSION

Conclusions

It was conducted to determine the relationship between the levels specific parameters such as IL-2, IL-12, and AMH and their effect on women with Toxoplasmosis, where the relationship was positive between the immune parameters, its levels increased in the event of infection, which increases possibility of using it as indicators of infection and also to predict the incidence of polycystic ovary syndrome or occurrence of infertility cases, there is a positive correlation between IL-2, IL-12 with level of AMH.