Behavioural brain research · 2023
Consumption of cashew nut induced anxiolytic-like behavior in dyslipidemic rats consuming a high fat diet.
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de Castro Querino Dias Celina, Madruga Marta Suely, Almeida Gabriel Henrique Oliveira, de Melo Marília Ferreira Frazão Tavares, Viera Vanessa Bordin, de Menezes Santos Bertozzo Camila Carolina, Dutra Larissa Maria Gomes, Alves Ana Paula Vilar, Dantas Francileide Amaro, Bezerra Jéssyka Kallyne Galvão, Soares Juliana Késsia Barbosa
Аннотация
This study aimed to evaluate the effect of cashew nut consumption on anxiety-like behavior in dyslipidemic rats. The groups formed were: Control (CONT), Dyslipidemic (DL) and Dyslipidemic cashew nuts (DLCN). Tests to assess anxiety parameters were performed after the treatment period. Brain fatty acid profiles were analyzed. The animals in the DLCN group showed more rearing than DL, without differing from the CONT and less grooming than either the DL and CONT in the Open Field. In the Elevated Plus Maze, DLCN spent more time on the open arms and in the central area compared to the other groups. As for brain fatty acids, there was a reduction in polyunsaturated fatty acids for the DLCN compared to the other groups. The cashew nut, rich in fatty acids, phenolic and flavonoid compounds, reduced the anxiogenic-like behavior caused by dyslipidemia in rats without altering brain fatty acids.