[Squamous cell carcinoma of the skin with bone involvement in hereditary dystrophic epidermolysis].

A report is given about a patient with a documented case history of hereditary dystrophic epidermiolysis over 43 years. The patient showed the rare malignant mutation resulting from chronic changes of the skin leading to a squamous cell carcinoma of the skin. The tibial bone under the affected skin area was attacked. The X-ray morphological findings of the osteolytic destruction of the tibia resulting in a pathological fracture and the changes in the skin, which are typical for the disease are discussed.