Nature human behaviour · 2023
Structural and functional asymmetry of the neonatal cerebral cortex.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Williams Logan Z J, Fitzgibbon Sean P, Bozek Jelena, Winkler Anderson M, Dimitrova Ralica, Poppe Tanya, Schuh Andreas, Makropoulos Antonios, Cupitt John, O'Muircheartaigh Jonathan, Duff Eugene P, Cordero-Grande Lucilio, Price Anthony N, Hajnal Joseph V, Rueckert Daniel, Smith Stephen M, Edwards A David, Robinson Emma C
Аннотация
Features of brain asymmetry have been implicated in a broad range of cognitive processes; however, their origins are still poorly understood. Here we investigated cortical asymmetries in 442 healthy term-born neonates using structural and functional magnetic resonance images from the Developing Human Connectome Project. Our results demonstrate that the neonatal cortex is markedly asymmetric in both structure and function. Cortical asymmetries observed in the term cohort were contextualized in two ways: by comparing them against cortical asymmetries observed in 103 preterm neonates scanned at term-equivalent age, and by comparing structural asymmetries against those observed in 1,110 healthy young adults from the Human Connectome Project. While associations with preterm birth and biological sex were minimal, significant differences exist between birth and adulthood.