The intravenous administration of equine antilymphocytic globulin in renal transplant recipients and the detection of circulating antibodies to equine globulin.

Methods are described for the intravenous administration of equine antilymphocytic globulin (ALG) to renal transplant recipients. The development of circulating antibodies to the equine IgG has been investigated using primary and secondary immunological procedures. The need for primary immunoassay procedures to assess both the immune response and induction of tolerance to equine IgG in ALG treated patients is extensively discussed.