Медицинская библиотека · Nutrition (Burbank, Los Angeles County, Calif.) · 2024

Peripheral fatty acids and outcome of assisted reproduction.

De Cosmi Valentina, Cipriani Sonia, Syren Marie-Louise, Turolo Stefano, Parazzini Fabio, Reschini Marco, Abodi Martina, Vegetti Walter, Chiaffarino Francesca, Bertoni Camilla, Somigliana Edgardo, Agostoni Carlo

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Аннотация

OBJECTIVES

The present study investigated the relationship between fatty acid levels in whole blood in women undergoing in vitro fertilization and four successive assisted reproductive technology (ART) outcomes.

METHODS

A cross-sectional study was performed on data from a prospective cohort study conducted between 2014 and 2016.

RESULTS

Participants were 238 women undergoing in vitro fertilization and participating in a study on the role of lifestyle habits and diet in ART outcomes. Blood polyunsaturated fatty acids were measured by gas chromatography. Overall, higher blood levels of monounsaturated fatty acids and oleic acid and higher ω-6/ω-3 ratio and arachidonic/docosahexaenoic acid ratio were associated with more favorable ART outcomes. By contrast, higher concentrations of long chain polyunsaturated fatty acids tended to be negatively associated with the considered outcomes.

CONCLUSIONS

Further prospective studies are needed to determine the ranges of fatty acid concentrations that are optimal for women with subfertility.

Для цитирования: De Cosmi Valentina, Cipriani Sonia, Syren Marie-Louise, Turolo Stefano, Parazzini Fabio, Reschini Marco, Abodi Martina, Vegetti Walter, Chiaffarino Francesca, Bertoni Camilla, Somigliana Edgardo, Agostoni Carlo. Peripheral fatty acids and outcome of assisted reproduction.. Nutrition (Burbank, Los Angeles County, Calif.). 2024. DOI: 10.1016/j.nut.2024.112616.

Предметные рубрики MeSH

Humans Female Adult Cross-Sectional Studies Prospective Studies Fertilization in Vitro Reproductive Techniques, Assisted Pregnancy Fatty Acids Fatty Acids, Unsaturated Treatment Outcome Fatty Acids, Omega-6

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