Revista espanola de salud publica · 2026
[Late-onset sequel states of poliomyelitis (postpolyomelitic syndrome)].
Аннотация на английскомСтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Rodríguez de Rivera Garrido Francisco Javier
Аннотация
OBJECTIVE: Poliomyelitis remains a Public Health challenge in countries with low vaccination coverage and outbreaks of vaccine-derived polioviruses. The aim of this paper was to review the current evidence on post-polio syndrome (PPS), including its pathophysiological basis, clinical manifestations, diagnostic criteria, and current therapeutic approaches.
METHODS: A narrative review of PubMed, Scopus, Web of Science, and World Health Organization documents was conducted, prioritizing systematic reviews, cohort studies, and clinical trials published between 1980 and 2024.
RESULTS: PPS affects 20-50% of polio survivors. It is characterized by progressive muscle weakness, fatigue, and pain decades after the initial infection. Its etiology remains unclear; proposed mechanisms include degeneration of reinnervated motor units, neuromuscular dysfunction, viral persistence, and autoimmunity. No pathogenetic treatments are available; management is symptomatic and multidisciplinary.
CONCLUSIONS: PPS is a chronic condition with high prevalence among poliomyelitis survivors. Current treatment focuses on rehabilitation, respiratory care, fatigue management, and psychological support. Further research is required to develop specific therapies.
METHODS: A narrative review of PubMed, Scopus, Web of Science, and World Health Organization documents was conducted, prioritizing systematic reviews, cohort studies, and clinical trials published between 1980 and 2024.
RESULTS: PPS affects 20-50% of polio survivors. It is characterized by progressive muscle weakness, fatigue, and pain decades after the initial infection. Its etiology remains unclear; proposed mechanisms include degeneration of reinnervated motor units, neuromuscular dysfunction, viral persistence, and autoimmunity. No pathogenetic treatments are available; management is symptomatic and multidisciplinary.
CONCLUSIONS: PPS is a chronic condition with high prevalence among poliomyelitis survivors. Current treatment focuses on rehabilitation, respiratory care, fatigue management, and psychological support. Further research is required to develop specific therapies.