A potential new use for gonadotropin-releasing hormone antagonists.

OBJECTIVE

To describe a potential new use of gonadotropin-releasing hormone (GnRH) antagonists.

DESIGN

Case report.

SETTING

Assisted conception unit at a teaching hospital in the United Kingdom.

PATIENT(S): A 37-year-old woman undergoing in vitro fertilization (IVF) who accidentally stopped using GnRH agonists after starting ovarian stimulation.

INTERVENTION(S): A GnRH antagonist was used to avoid a luteinizing hormone (LH) surge and hence "rescue" the cycle.

RESULT(S): Successful oocyte retrieval was carried out, two embryos transferred, and a viable twin pregnancy ensued.

CONCLUSION(S): This may be a new indication for the use of GnRH antagonists.