[Systemic lupus erythematosus (SLE)].

Systemic lupus erythematosus (SLE) is a connective tissue disease ranked as an autoimmune background illness. Due to the fact, that 90% of lupus suffering patients are women in childbearing age, SLE is relatively common in pregnancy. SLE exerts negative influence on pregnancy course and perinatal period, significantly increasing a risk of spontaneous abortions, intrauterine fetal growth restrictions, fetal mortality in second trimester and premature labour. The increase of perinatal mortality is usually a consequence of diffuse nephritis, hypertension or presence of antiphospholipid antibodies. Women with SLE belong to high-risk pregnancy group, need special care and delivery should take place in hospital conditions exclusively. In our paper we present an epidemiological aspect and complicated issue of diagnostic and therapeutic approaches of pregnant women suffering from SLE with special focus on current care standards and treatment recommendations.