[Determination of beta-hexosaminidase and gamma-glutamyltranspeptidase activities in urine of pregnant women to monitor alcohol consumption].

BACKGROUND

Drinking of alcohol by pregnant women provokes many fetal development disorders, first of all the function of central nervous system and can lead to Fetal Alcohol Syndrome - FAS.

AIM: Aims of investigation were to determine beta - hexosaminidase (HEX) and gamma - glutamyltranspeptidase (GGT) activity in the urine to monitoring consumption of alcohol by pregnant women in first trimester and to assess the effect of ethyl alcohol on fetus development.

MATERIAL AND

METHODS

22 pregnant women, who did not declare consumption of ethanol containing drinks. The level of creatinine, GGT and HEX in urine was analysed.

RESULTS

Preliminary results of our study indicate that determination of GGT and HEX activities could be useful in monitoring of alcohol consumption during pregnancy.