Corrigendum: Survival After Simultaneous Pancreas-Kidney Transplantation in Type 1 Diabetes: The Critical Role of Early Pancreas Allograft Function.

INTRODUCTION

Varicella-zoster virus (VZV) remains an occupational hazard for healthcare workers (HCWs), yet serological screening and catch-up vaccination policies are inconsistently implemented. We aimed to estimate VZV IgG seroprevalence and vaccination coverage among Greek HCWs, assess the validity of self-reported immunity, and explore the feasibility and yield of brief cognitive screening in this population.

METHODS

In this cross-sectional study, physicians, nurses, paramedical and administrative staff completed a standardized questionnaire on demographic characteristics, varicella/herpes zoster history and vaccination. Serum VZV immunoglobulin G (IgG) was measured using a commercial enzyme-linked immunosorbent assay. Agreement between self-reported immunity and serostatus was quantified with Cohen's κ. Cognitive performance was assessed with the General Practitioner Assessment of Cognition (GPCOG) in an exploratory analysis.

RESULTS

Seventy-four HCWs (mean age 40.8 years; 67.6% female) were enrolled; 77.0% reported prior varicella vaccination and 4.1% reported herpes zoster vaccination. VZV IgG seroprevalence was 93.2% (6.8% seronegative). Self-reported immunity showed high crude agreement but no concordance beyond chance with serostatus (κ=0.03), with 14.9% underestimating and 5.4% overestimating their immunity. GPCOG step 1 scores were strongly skewed to the maximum (mean 8.77/9), yielding marked ceiling effects and no detectable association with VZV markers in exploratory analyses.

CONCLUSION

In this sample of Greek HCWs, VZV immunity was high but not universal, and self-reported history was an unreliable proxy for serological status. Our findings support serological screening and targeted vaccination of susceptible HCWs for infection-control purposes. Cognitive screening with GPCOG in this relatively young workforce showed minimal discrimination and should be considered exploratory. These findings are particularly relevant to rural and remote health services, where limited staffing flexibility can magnify the impact of susceptible healthcare workers on service continuity and infection control.