Медицинская библиотека · Wei sheng yan jiu = Journal of hygiene research · 2015

[Meta-analysis of relationship between maternal formaldehyde exposure during pregnancy and spontaneous abortion].

Chen Chen, Cheng Yibin

Аннотация на английскомСтатьяМетаанализПеревод в очереди

Аннотация

OBJECTIVE

To evaluate the relationship between maternal formaldehyde exposure during pregnancy and spontaneous abortion.

METHODS

A computerized literature search was carried out to collect articles published before 2014. The study types included case-control and cohort studies. And then the statistical analysis was conducted by using RevMan 5. 1 software.

RESULTS

A total of 6 studies were included in Meta-analysis (totally 666 subjects and 3087 controls) according to the selection criteria. Because all the studies selected were homogeneous (I2 = 37% , P = 0. 16) , the fixed effect model was used for calculation of the combined OR values. Compared with the control, maternal formaldehyde exposure during pregnancy was significantly associated with spontaneous abortion (OR = 1. 64, 95% CI 1. 20 - 2. 24, P = 0. 002).

CONCLUSION

Maternal formaldehyde exposure during pregnancy may increase the risk of spontaneous abortion.

Для цитирования: Chen Chen, Cheng Yibin. [Meta-analysis of relationship between maternal formaldehyde exposure during pregnancy and spontaneous abortion].. Wei sheng yan jiu = Journal of hygiene research. 2015.

Предметные рубрики MeSH

Abortion, Spontaneous Female Formaldehyde Humans Maternal Exposure Pregnancy Respiratory Hypersensitivity

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