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DOI 10.1371/journal.pone.0226132

Медицинская библиотека · PloS one · 2019

Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report.

Haslacher Helmuth, Fallmann Hannelore, Waldhäusl Claudia, Hartmann Edith, Wagner Oswald F, Waldhäusl Werner

СтатьяНаблюдательное исследованиеПеревод в очереди

Аннотация

BACKGROUND

Outcome of type 2 diabetes care depends on the acceptance of self-responsibility by informed patients, as treatment goals will otherwise be missed.

AIMS AND

METHODS

This pre/post-observational report describes the clinical outcome of type 2 diabetes care in patients with type 2 diabetes (N =930) admitted consecutively to a diabetes rehabilitation clinic (DRC) between June 2013, and June 2016, where they were exposed to standardized lifestyle modification with meals low in salt and rich in vegetables and fruits, totaling 1,200 to 1,600 kcal/d, and an add-on exercise load equivalent to 400-600 kcal/d.

RESULTS

At admission, patients presented with multiple treatment modes, elevated HbA1c levels (7.6±1.5%, 60±16 mmol/mol), a high prevalence of co-morbidities dominated by obesity (79%), a low rate of influenza and pneumococcal immunization (<9%) and underuse of lipid-lowering drugs (-29%). Analysis of clinical and metabolic outcome after 3 weeks shows that simple standardization of and better adherence to treatment recommendations improved (p<0.0001) glucose (HbA1c -0.4±0.4%) and lipid metabolism (LDL/HDL ratio, -0.58±0.03), permitting a 39% reduction in insulin dosage, omission of insulin in 36/232 patients and omission of oral antidiabetic drugs (OADs) other than metformin and DPP4-inhibitors, while the use of GLP-1 analogs doubled to 5.2%. Improved outcome was independent of treatment strategy and more marked at initially high HbA1c at costs less than 25% of those encountered at a standard hospital.

CONCLUSIONS

Our observations support the clinical notion that adherence to basic treatment recommendations is indispensable in type 2 diabetes care if metabolic and clinical treatment goals are to be met, and if inappropriate add-on over-medicalization with OADs and/or insulin is to be avoided. To this end, 'imprinting' patients at a DRC could be of considerable help.

Для цитирования: Haslacher Helmuth, Fallmann Hannelore, Waldhäusl Claudia, Hartmann Edith, Wagner Oswald F, Waldhäusl Werner. Type 2 diabetes care: Improvement by standardization at a diabetes rehabilitation clinic. An observational report.. PloS one. 2019. DOI: 10.1371/journal.pone.0226132.

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