Psychosis and Delirium as Manifesting Symptoms of Chronic and Heavy Nitrous Oxide Use in a 37-Year-Old Samoan Male Patient: A Case Report.

Nitrous oxide (N2O) is a clear gas used in the food industry as well as in clinical settings as an analgesic and anesthetic agent. It is also a commonly used recreational drug due to its anxiolytic and euphoric effects. We discuss the case of a 37-year-old Samoan male with a long-standing history of N2O use who was brought to the emergency department for psychotic symptoms, which expanded to symptoms of delirium soon after his presentation. This case report adds to the literature about N2O-induced psychiatric presentations, particularly by focusing on a patient from an underrepresented population. We outline his clinical presentation, describe the presenting physical and psychiatric symptoms, and discuss management options based on existing literature and knowledge. The patient's information is adequately de-identified in this case report.