Carbon dioxide laser-assisted bone regenerative therapy without membrane use.

Favorable outcomes have been reported with periodontal regeneration therapies using dental lasers for blood clot formation. Herein, we presented the clinical and radiographic outcomes of carbon dioxide laser-assisted bone regenerative therapy (LBRT) in periodontology. A 60-year-old man presented with mobility in teeth 43 and 44. Accordingly, the extraction of tooth 44 and periodontal regeneration using carbon dioxide-LBRT around tooth 43 were planned. After thorough debridement, enamel matrix derivative and carbonated apatite (CA) were applied to the root surface and bone defects, respectively. Thereafter, the filled blood-mixed CA was irradiated using a carbon dioxide laser to accelerate blood clot formation for stabilizing the bone graft. At the 13-month follow-up, significant improvements in clinical parameters were observed, indicating substantial bone regeneration. In this patient, the excellent clinical and radiographic healing demonstrated the efficacy of carbon dioxide-LBRT for periodontal regeneration. Blood clot formation using a carbon dioxide laser may lead to favorable outcomes.