Predictors of intraoperative complications in men undergoing inflatable penile prosthesis placement.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Jones James M, Barham David W, Gross Martin S, Chang Chrystal, Hammad Muhammed, Swerdloff Daniel, Miller Jake, Loeb Charles, Andrianne Robert, Burnett Arthur L, Gross Kelli, Hatzichristodoulou Georgios, Hotaling James M, Hsieh Tung-Chin, Jenkins Lawrence C, Jones Adam, Lentz Aaron C, Modgil Vaibhav, Osmonov Daniar, Park Sung H, Pearce Ian, Perito Paul, Sadeghi-Nejad Hossein, Sempels Maxime, Suarez-Sarmiento Alfredo, Simhan Jay, van Renterghem Koenraad, Warner Jonathan Nicholas, Ziegelmann Matthew, Yafi Faysal A, On Behalf Of The Pump Prosthetic Urology Multi-Institutional Partnership Collaborators
Аннотация
AIM: To evaluate the association between history of ICI, history of prostate cancer treatment (prostatectomy, radiation) and complications of inflatable penile prosthesis (IPP) placement.
METHODS: A retrospective cohort study was performed of primary IPP cases from 2016 to 2021 across 16 institutions. Patients were stratified by development of intraoperative complications (crossover, corporal perforation, or urethral injury) and between-group differences in risk factors were assessed. Multivariable logistic regression was used to assess for predictors of intraoperative complications and postoperative infection.
OUTCOMES: The primary outcome was intraoperative complications, and secondary outcome was implant infection.
RESULTS: A total of 2540 patients met inclusion criteria. Intraoperative complications occurred in 36 (1.4%) patients. On multivariable regression, a history of ICI, prostatectomy, and radiation were all significant predictors of intraoperative complications (OR 2.11, P = 0.03; OR 2.27, P = 0.03; OR 2.40, P = 0.04, respectively). Age, body mass index, diabetes, hypertension, vascular disease, smoking, and Peyronie's disease were not predictors of intraoperative complications. None of the variables were significant predictors of infection.
CLINICAL IMPLICATIONS: Prosthetic urologists should counsel patients that a history of ICI or prostate cancer treatment with radical prostatectomy and/or radiation are associated with an increased risk of intraoperative complications.
STRENGTHS AND LIMITATIONS: Strengths of this study include the utilization of a large, multicenter, international dataset. The study is limited by retrospective nature, a lack of granular data as to the type and duration of ICI therapy, and inherent selection bias in that all cases were performed by dedicated implant surgeons.
CONCLUSION: In men undergoing IPP placement, a history of ICI, a history of radical prostatectomy, and a history of radiation are all independently associated with increased risk of intraoperative complications.