Infectious medicine · 2023
The role of SARS-COV-2 infection in promoting abnormal immune response and sepsis: A comparison between SARS-COV-2-related sepsis and sepsis from other causes.
СтатьяНазвание и аннотация: Перевод в очереди
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Piccioni Andrea, Franza Laura, Rosa Federico, Candelli Marcello, Covino Marcello, Ferrara Michela, Volonnino Gianpietro, Bertozzi Giuseppe, Vittoria Zamponi Maria, Maiese Aniello, Savioli Gabriele, Franceschi Francesco, La Russa Raffaele
Аннотация
BACKGROUND: COVID-19 caused by SARS-CoV-2 virus is characterized by respiratory compromise and immune system involvement, even leading to serious disorders, such as cytokine storm.
METHODS: We then conducted a literature review on the topic of sepsis and covid-19, and in parallel conducted an experimental study on the histological finding of patients who died from SARS-Covid 19 infection and a control group.
RESULTS: Sepsis associated with covid-19 infection has some similarities and differences from that from other causes.
CONCLUSION: In this paper the complex interplay between the 2 disorders was discussed, focusing on the similarities and on the effect that one could have on the other. A preliminary experimental section that demonstrates the multisystemic involvement in subjects who die from SARS-CoV-2 is also proposed.
METHODS: We then conducted a literature review on the topic of sepsis and covid-19, and in parallel conducted an experimental study on the histological finding of patients who died from SARS-Covid 19 infection and a control group.
RESULTS: Sepsis associated with covid-19 infection has some similarities and differences from that from other causes.
CONCLUSION: In this paper the complex interplay between the 2 disorders was discussed, focusing on the similarities and on the effect that one could have on the other. A preliminary experimental section that demonstrates the multisystemic involvement in subjects who die from SARS-CoV-2 is also proposed.