Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control · 2014
[Toxoplasma gondii infection status in abnormal pregnancy women].
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Zhang Shu-fang, Song Ren-hao
Аннотация
OBJECTIVE: To investigate the relationship between Toxoplasma gondii (TOX) infection and abnormal pregnancy outcomes.
METHODS: A total of 126 cases of abnormal pregnancy women in the Department of Obstetrics and Gynecology, the Fourth People' s Hospital of Langfang from March to December 2013 were chosen as an experimental group, and 263 cases of normal pregnancy women of childbearing age as a control group. The TOX-IgM and -IgG antibodies were detected by ELISA. The data in the two groups were processed and analyzed by SPSS13.0.
RESULTS: The positive rates of TOX-IgM, -IgG in 126 cases of abnormal pregnancy women were 7.94% and 19.84% respectively, and 1.90% and 8.75% in the control group respectively, and there were significant differences between them (χ2IgM = 6.82, χ2IgG = 9.70, both P <0.01). The positive rates of TOX-IgM, -IgG in the normal pregnancy women were lower than those in 4 sub-groups of abnormal pregnancy women, and all the differences were statistically significant (χ2 spontaneous abortion = 10.40, χ2 premature delivery = 9.03 χ2 embryo damage = 4.32, χ2 birth defet = 4.04, all P< 0.05). However, the TOX-IgM, -IgG positive rates in the 4 sub-groups of abnormal pregnancy women had no statistically significant difference (P > 0.05).
CONCLUSIONS: TOX infection could cause serious abnormal pregnancy outcomes. Therefore, the comprehensive control measures should be strengthened.
METHODS: A total of 126 cases of abnormal pregnancy women in the Department of Obstetrics and Gynecology, the Fourth People' s Hospital of Langfang from March to December 2013 were chosen as an experimental group, and 263 cases of normal pregnancy women of childbearing age as a control group. The TOX-IgM and -IgG antibodies were detected by ELISA. The data in the two groups were processed and analyzed by SPSS13.0.
RESULTS: The positive rates of TOX-IgM, -IgG in 126 cases of abnormal pregnancy women were 7.94% and 19.84% respectively, and 1.90% and 8.75% in the control group respectively, and there were significant differences between them (χ2IgM = 6.82, χ2IgG = 9.70, both P <0.01). The positive rates of TOX-IgM, -IgG in the normal pregnancy women were lower than those in 4 sub-groups of abnormal pregnancy women, and all the differences were statistically significant (χ2 spontaneous abortion = 10.40, χ2 premature delivery = 9.03 χ2 embryo damage = 4.32, χ2 birth defet = 4.04, all P< 0.05). However, the TOX-IgM, -IgG positive rates in the 4 sub-groups of abnormal pregnancy women had no statistically significant difference (P > 0.05).
CONCLUSIONS: TOX infection could cause serious abnormal pregnancy outcomes. Therefore, the comprehensive control measures should be strengthened.