Isograft bladder mucosal transplantation for hypospadias repair in identical twins.

Urethral reconstruction with a bladder mucosal free graft offers several advantages for patients with complex hypospadias. We report a case in which identical twins circumcised at birth presented with mid-shaft hypospadias and chordee. A bladder mucosa graft was harvested from 1 twin, divided and used to form 2 neourethras. The donor twin underwent hypospadias repair, followed immediately by repair in the second twin with the isograft neourethra. To our knowledge this is the first reported case of bladder mucosal transplantation for hypospadias repair.