[Antibiotic administration in preterm delivery].

DESIGN

Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor.

OBJECTIVES

We attempted to determine the effect of antibioticotherapy in mothers on congenital neonatal infection.

MATERIALS AND

METHODS

The study group consisted of 1049 pregnant women with imminent preterm labor hospitalized in Clinics of The Research Institute Polish Mother's Memorial Hospital.

RESULTS

244 women delivered preterm and no significant difference in neonatal outcomes could be detected in two groups with intact membranes and preterm premature rupture of membranes.

CONCLUSIONS

The results of this study do not support the routine use of antibiotic administration in women with preterm labor.