Autosomal dominant polycystic kidney disease and hypertension in the aviator.

Autosomal dominant polycystic kidney disease is a relatively common familial disorder which frequently affects multiple organ systems. The condition is associated with hypertension, cardiac valvular abnormalities, cerebral berry aneurysms, and chronic renal failure. We describe an aviator with a long history of hypertension that was found to be due to autosomal dominant polycystic kidney disease. Following an extensive evaluation, he was found capable of continuation of flying duties. The epidemiology, pathogenesis, diagnosis, evaluation, and aeromedical implications of autosomal dominant polycystic kidney disease in an aviator are discussed.