Urologiia (Moscow, Russia : 1999) · 2025
[Comparative analysis of the results of morphological examination of hyperplastic prostate tissue in patients with and without testosterone deficiency].
СтатьяСравнительное исследованиеАннотация на английскомНазвание и аннотация: Перевод в очереди
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Ibishev Kh S, Lemeshko S I, Uzhakhov M M H, Kogan M I
Аннотация
INTRODUCTION: Benign prostatic hyperplasia (BPH) is an important and urgent public health problem. Prostatic hyperplasia is characterized by epithelial, stromal, and muscular proliferation.
OBJECTIVE: To conduct a comparative analysis of the results of morphological examination of resected prostate tissue in patients with prostatic hyperplasia with and without testosterone deficiency.
MATERIALS AND METHODS: The results of morphological examination of the resected prostate tissue of 188 men with BPH were analyzed, who were divided into two groups: Group I - 71 patients with testosterone deficiency, group II (control) - 117 patients with testosterone levels above 12.1 nmol/L.
RESULTS: In patients with testosterone deficiency, during morphological examination of resected pancreatic tissue samples, prostate hyperplasia had a diffuse stromal character, combined with cystic deformity of the acinuses, with flattened and unclassifying epithelium, against the background of basal cell hyperplasia. In patients with normal Tc levels during morphological examination, during morphological examination of resected pancreatic tissue samples, the hyperplasia in all patients was glandular (epithelial), and the epithelial cells of the acinuses were tall cylindrical, with signs of active secretion.
CONCLUSION: In hypogonadal men, stromal hyperplasia was detected in most cases (76.1%) in the resected prostate tissue, and in normogonadal patients, hyperplasia was glandular in all cases.
OBJECTIVE: To conduct a comparative analysis of the results of morphological examination of resected prostate tissue in patients with prostatic hyperplasia with and without testosterone deficiency.
MATERIALS AND METHODS: The results of morphological examination of the resected prostate tissue of 188 men with BPH were analyzed, who were divided into two groups: Group I - 71 patients with testosterone deficiency, group II (control) - 117 patients with testosterone levels above 12.1 nmol/L.
RESULTS: In patients with testosterone deficiency, during morphological examination of resected pancreatic tissue samples, prostate hyperplasia had a diffuse stromal character, combined with cystic deformity of the acinuses, with flattened and unclassifying epithelium, against the background of basal cell hyperplasia. In patients with normal Tc levels during morphological examination, during morphological examination of resected pancreatic tissue samples, the hyperplasia in all patients was glandular (epithelial), and the epithelial cells of the acinuses were tall cylindrical, with signs of active secretion.
CONCLUSION: In hypogonadal men, stromal hyperplasia was detected in most cases (76.1%) in the resected prostate tissue, and in normogonadal patients, hyperplasia was glandular in all cases.