The Unusual Actinotigum schaalii (Formerly Named Actinobaculum schaalii) Bacteremia.

BACKGROUND

This study aimed to evaluate unusual case reports about Actinotigum schaalii (A. schaalii) bacteremia patients in the past 20 years.

METHODS

A retrospective review of A. schaalii bacteremia patients collected from MEDLINE between January 2005 and November 2024.

RESULTS

Of 34 cases, the identification (ID) of A. schaalii for clinical samples included blood (n = 34), urine (n = 6), valve (n = 1), and biopsy (n = 1). Polymicrobial infections were 32.4% (n = 11 out of 34) in this study. Antimicrobial susceptibility tests (ASTs) were performed in most cases. The A. schaalii isolates were sensitive to penicillin, β-lactam combination agent, lincosamide, tetracycline, nitrofuran, cephem, carbapenem, oxazolidinone, ansamycin, macrolide, and glycylcycline; but resistant to fluoroquinolone, nitroimidazole, aminoglycoside, and folate pathway antagonists.

CONCLUSIONS

Microbiologists should perform the correct ID and suitable AST of the potentially invasive A. schaalii to help clinicians obtain the appropriate antimicrobial coverage for serious systemic infections.