Der Urologe. Ausg. A · 2013
[Sentinel lymph node biopsy for penile carcinoma : Assessment of reliability].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Fuchs J, Hamann M F, Schulenburg F, Knüpfer S, Osmonov D, Lützen U, Jünemann K-P, Naumann C M
Аннотация
BACKGROUND: The European Association of Urologists recommends dynamic sentinel node biopsy (DSNB) as the first choice diagnostic approach for lymph node staging of non-palpable inguinal lymph nodes in penile carcinoma. The aim of this study was to assess the reliability of minimally invasive inguinal DSNB.
MATERIAL AND METHODS: Between 2004 and 2012 DSNB was used in all patients with invasive penile carcinoma and non-palpable inguinal lymph nodes. For assessment of reliability the rate of false negative results was determined and complications were documented. The results were analyzed prospectively.
RESULTS: In the study period DSNB was performed in a total of 29 patients and it was possible to prove lymph node metastasis in 2 patients with 1 patient who developed lymph node metastasis after a negative DSNB. Thus the false negative rate was 3.70 %. A morbidity rate of 3.45 % was also observed.
CONCLUSION: Sentinel lymph node biopsy is a reliable diagnostic method. The sophisticated requirements both methodologically and logistically suggest that this procedure should only be performed in specialized centres.
MATERIAL AND METHODS: Between 2004 and 2012 DSNB was used in all patients with invasive penile carcinoma and non-palpable inguinal lymph nodes. For assessment of reliability the rate of false negative results was determined and complications were documented. The results were analyzed prospectively.
RESULTS: In the study period DSNB was performed in a total of 29 patients and it was possible to prove lymph node metastasis in 2 patients with 1 patient who developed lymph node metastasis after a negative DSNB. Thus the false negative rate was 3.70 %. A morbidity rate of 3.45 % was also observed.
CONCLUSION: Sentinel lymph node biopsy is a reliable diagnostic method. The sophisticated requirements both methodologically and logistically suggest that this procedure should only be performed in specialized centres.