Interventions to prevent bloodstream infections associated with central venous access devices: Priorities for an adaptive platform trial.

Health care-associated bloodstream infections are serious complications of central venous access devices. Numerous preventative interventions exist, but without high-level evidence. The IVCare adaptive platform trial will provide multiple answers for infection prevention. A prioritization study with infection preventionists using the Society for Healthcare Epidemiology of America central line-associated bloodstream infection prevention framework identified priorities for IVCare intervention testing as: vascular access teams, education/competency for central venous access device insertion/postinsertion care, sutureless securement, connector type and decontamination method.