Does Intramedullary Nail Fixation of the Tibia Pose the Same Risk of Pulmonary Complications as Intramedullary Nail Fixation of the Femur? A Propensity Score-Matched Analysis.

OBJECTIVES

To compare duration of mechanical ventilation and pulmonary outcomes in patients treated with intramedullary nail (IMN) fixation of the tibia versus the femur.

DESIGN

Retrospective cohort study.

SETTING

Level I trauma center.

PATIENTS: One thousand thirty patients were categorized based on treatment: those treated with IMN of the tibia (n = 515) and those treated with IMN of the femur (n = 515).

INTERVENTION: IMN fixation of tibial and femoral fractures.

OUTCOME MEASUREMENTS: The primary outcome was duration of mechanical ventilation. Secondary outcomes included length of intensive care unit (ICU) stay and risk of tracheostomy, pulmonary embolism (PE), acute respiratory distress syndrome (ARDS), and mortality.

RESULTS

In an unadjusted analysis, femoral fractures were associated with increase in ventilator days (mean difference, 1.4; P < 0.001), ICU days (mean difference, 1.8; P < 0.001), and odds of tracheostomy (odds ratio, 1.7; P < 0.01). No difference was shown in likelihood of PE, ARDS, or mortality (P > 0.2). Propensity score-matched estimates showed no differences in any measured outcomes (P > 0.40). In patients with Injury Severity Scores >17, we found no difference in length of ventilator or ICU days or likelihood of tracheostomy, PE, ARDS, or mortality in the unadjusted (P > 0.2) or propensity score-matched estimates (P > 0.3).

CONCLUSIONS

These findings suggest that IMN fixation of the tibia is associated with duration of mechanical ventilation and risk of poor pulmonary outcomes similar to those of femoral nailing, after adjustment for baseline characteristics.

LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.