Fertility and sterility · 2004
A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection.
Клиническое исследованиеСравнительное исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Perino Antonio, Castelli Antonio, Cucinella Gaspare, Biondo Andrea, Pane Antonella, Venezia Renato
Аннотация
OBJECTIVE: To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation procedure, versus transcervical hysteroscopic endometrial resection (TCRE).
DESIGN: Randomized clinical study. Healthy volunteers in an academic research environment.
SETTING: Academic teaching hospital.
PATIENT(S): Premenopausal women with abnormal uterine bleeding.
INTERVENTION(S): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure.
MAIN OUTCOME MEASURE(S): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate.
RESULT(S): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure.
CONCLUSION(S): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.
DESIGN: Randomized clinical study. Healthy volunteers in an academic research environment.
SETTING: Academic teaching hospital.
PATIENT(S): Premenopausal women with abnormal uterine bleeding.
INTERVENTION(S): Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure.
MAIN OUTCOME MEASURE(S): Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate.
RESULT(S): At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure.
CONCLUSION(S): Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.