The American journal of medicine · 1995
Long-term follow-up of endoscopic retrograde cholangiopancreatography sphincterotomy for patients with acquired immune deficiency syndrome papillary stenosis.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Cello J P, Chan M F
Аннотация
PURPOSE: To evaluate the long-term effects on biliary-type pain and changes in biochemical parameters in patients with AIDS-associated papillary stenosis who underwent endoscopic retrograde cholangiopancreatography (ERCP) sphincterotomy.
PATIENTS AND METHODS: Twenty-five consecutive patients were diagnosed by cholangiography with AIDS-associated papillary stenosis using standard criteria. Patients underwent ERCP sphincterotomy and were followed prospectively in the Gastrointestinal or Liver Clinics, San Francisco General Hospital, and by their primary physicians. Post-procedure data was prospectively collected by chart review or in-person or telephone interview, and analyzed using statistical software.
RESULTS: All patients presented with severe right upper quadrant and/or mid-epigastric abdominal pain and had marked elevations of serum alkaline phosphatase. Following ERCP sphincterotomy, pain scores decreased significantly for at least 9 months of follow-up. Serum alkaline phosphatase levels, however, remained essentially unchanged. Overall quality of life was difficult to assess, as patients suffered from other AIDS-associated debilitating diseases.
CONCLUSIONS: ERCP sphincterotomy, while not without risks, provided significant reduction in pain in patients with AIDS-associated papillary stenosis.
PATIENTS AND METHODS: Twenty-five consecutive patients were diagnosed by cholangiography with AIDS-associated papillary stenosis using standard criteria. Patients underwent ERCP sphincterotomy and were followed prospectively in the Gastrointestinal or Liver Clinics, San Francisco General Hospital, and by their primary physicians. Post-procedure data was prospectively collected by chart review or in-person or telephone interview, and analyzed using statistical software.
RESULTS: All patients presented with severe right upper quadrant and/or mid-epigastric abdominal pain and had marked elevations of serum alkaline phosphatase. Following ERCP sphincterotomy, pain scores decreased significantly for at least 9 months of follow-up. Serum alkaline phosphatase levels, however, remained essentially unchanged. Overall quality of life was difficult to assess, as patients suffered from other AIDS-associated debilitating diseases.
CONCLUSIONS: ERCP sphincterotomy, while not without risks, provided significant reduction in pain in patients with AIDS-associated papillary stenosis.