European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
Clinical characteristics and prognostic risk factors of candidemia in non-neutropenic patients: a retrospective cohort study.
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Liu Fengqi, Shao Xueping, Dong Zhaohui, Tang Kankai, Zhong Li, Xu Wei, Chen Zhidong, Zheng Cheng, Zhang Kai, Cai Jiachang, Zhou Hongwei, Cui Wei, Xie Chuangao, Zhang Liangfeng, Zhang Gensheng
Аннотация
This study aimed to determine the clinical characteristics and the prognostic risk factors in non-neutropenic patients with candidemia. Data were retrospectively collected through the medical record information system. Non-neutropenic patients with candidemia were relatively aged, with a more than one-third rate of in-hospitalization mortality. In multivariate analysis, APACHE II score (adjusted odds ratio [aOR], 1.138; 95% confidence interval [CI], 1.067-1.213), septic shock (aOR, 5.704; 95% CI, 2.639-12.326) and RRT (aOR, 16.152; 95% CI, 2.628-99.275) (all P < 0.01) were independent related with non-survivors. In conclusion, non-neutropenic patients with candidemia have a high in-hospitalization mortality, and APACHE II, septic shock, and RRT are independently factors.