Journal of psychosomatic research · 2025
Impact of consultation liaison services on postoperative psychotropic drug use.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Kitaoka Riki, Ayani Nobutaka, Uramatsu Takahiro, Yamazoe Eriko, Okazaki Tomoya, Ogawa Kyohei, Yokoi Takato, Takeda Keisuke, Nakai Koju, Oya Nozomu, Nakamura Takeshi, Horiguchi Go, Narumoto Jin
Аннотация
OBJECTIVE: In clinical practice, most cases of postoperative delirium are treated by an attending surgeon who is not a specialist in delirium treatment. We investigated the postoperative use of psychotropic drugs with and without psychiatric consultation liaison service (CLS).
METHOD: Patients who received specific psychotropic drugs postoperatively under general anesthesia were included. The participants were divided into two groups, with and without CLS intervention. The type and dosage of psychotropic drugs used, presence of delirium, and adverse drug events (ADEs) caused by psychotropic drugs administered postoperatively were investigated.
RESULTS: Of the 509 patients who were newly prescribed the psychotropic drugs postoperatively, 67 patients (13 %) received CLS intervention. In the non-CLS group, 65 % (43/66) of patients who received antipsychotics after surgery did not have delirium, which was significantly higher than in the CLS group (65 % vs 22 %, p < 0.01). Haloperidol was the most commonly used antipsychotic postoperatively, and the median daily dose was significantly higher in the non-CLS group (0.22 mg/day vs 0.38 mg/day, p = 0.04).
CONCLUSION: CLS interventions may contribute to a reduction in unnecessary administration of antipsychotic drugs and dosages.
METHOD: Patients who received specific psychotropic drugs postoperatively under general anesthesia were included. The participants were divided into two groups, with and without CLS intervention. The type and dosage of psychotropic drugs used, presence of delirium, and adverse drug events (ADEs) caused by psychotropic drugs administered postoperatively were investigated.
RESULTS: Of the 509 patients who were newly prescribed the psychotropic drugs postoperatively, 67 patients (13 %) received CLS intervention. In the non-CLS group, 65 % (43/66) of patients who received antipsychotics after surgery did not have delirium, which was significantly higher than in the CLS group (65 % vs 22 %, p < 0.01). Haloperidol was the most commonly used antipsychotic postoperatively, and the median daily dose was significantly higher in the non-CLS group (0.22 mg/day vs 0.38 mg/day, p = 0.04).
CONCLUSION: CLS interventions may contribute to a reduction in unnecessary administration of antipsychotic drugs and dosages.